πͺπ²π²πΈπΉπ π¦π½πΌππΉπΆπ΄π΅π #12 π’
Patient-Centric drug product design in modern drug delivery as an opportunity to increase safety and effectiveness
The advances in drug delivery technologies have enabled pharmaceutical scientists to deliver drugs through various administration routes while optimizing drug release and absorption. A wide range of drug delivery systems and dosage forms are available for product development. Exposure to such diversity may increase patient confusion, leading to medication errors and nonadherence. To mitigate this, patient-centric drug product development has been increasingly suggested as a key factor to improve therapeutic outcomes. π
Patients have impaired health and potential disabilities. They are requested to manage complex therapeutic regimens while being no pharmaceutical or medical experts. Therefore, pharmaceutical development should be built on patients' intuition and ease of use to reduce regimen complexity. π΄
Establishing a target product and patient profile is essential to guide drug product development. Including the targeted patient populations is a prerequisite to promoting patient-centric pharmaceutical drug product design. Addressing patients' needs early in the product design process will create a more universal design, avoiding the necessity for multiple product presentations to cover the different patient populations. β
π Reference:
S. Segemann, Patient centric drug product design in modern drug delivery as an opportunity to increase safety and effectiveness. Expert Opin Drug Deliv. 2018 Jun;15(6):619-627.